Universal fixative for histological specimens ready to use.
A maximum of 5 pieces can be ordered
The 10% formalin neutral buffered (equivalent to an aqueous solution of 4% formaldehyde) is the fixative most commonly used in the histopathological routine. The interaction between formaldehyde and functional groups present in tissue macromolecules (proteins and nucleic acids) occurs according to the following scheme:
formation of methylene glycol: the molecule of formaldehyde in water gives rise to the following equilibrium: CH2O + H2O = CH2(OH)2
The methylene glycol is the chemical species that interacts primarily with the functional groups present in the side chains of the proteins and with acids stabilizing the nuclear structure.
secondarily formaldehyde form crosslinks between the free amino groups present in the side chains of amino acids.
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Product for the preparation of cyto-histological samples for optical microscopy. Quick method for differential staining of formed blood elements. It can also be used to stain other types of air-dried smears (sediment smears, needle aspirates). The resulting staining can be compared to traditional May Grunwald-Giemsa method.
2 bottles of reagent A + 1 bottle of reagent B + 1 bottle of reagent C
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Universal fixative for histological specimens ready to use.
